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Recent advanced in the medical treatment of melanoma

21 giugno 2013
Sede del Corso:
Domus Nova Bethlem - Roma

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RAZIONALE

Cutaneous malignant melanoma (CMM) remains one of the few malignancies that exhibit an increased rate in the developed world. Its incidence in fact has accelerated to become a major disease in women under the age of 40, surpassing even breast cancer. The major etiologic risk factor for CMM is thought to be exposure to intermittent erythemogenic doses of UV, especially during childhood and early adolescence in subject with risk phototype and genetic predisposition. In view of this, CMM is a malignancy which can highly benefit from prevention and early diagnosis. Although the two strategies has resulted in the increased detection of highly curable low risk (thin) lesions, the management of more advance disease of known resistance to treatments has remained a challenge for a long time. This scenario is now undergoing a steady improvement in view of the results of genetic and molecular analysis, the development of target therapies and of more efficacious immunotherapeutic regimens. Despite these advancements, still a large fraction of patients relapse, thus research into response and resistance mechanisms, rationally designed combination therapies and evaluation of the role of these agents in the adjuvant setting need to be addressed.

PROGRAMMA

10.00 – 10.15
Registration

10.15 – 10.30
Course presentation
P.G. Natali (Roma)

10.30 – 13.00
Genetic Testing, Counseling, and Adherence to Skin Cancer Prevention and Detection Behaviors
SERIE DI RELAZIONI SU TEMA PREORDINATO
V. Ramazzotti (Roma)

Melanoma molecular classes and prognosis in the postgenomic era
SERIE DI RELAZIONI SU TEMA PREORDINATO
P. Giacomini (Roma)

From chemotherapy to targeted treatment
SERIE DI RELAZIONI SU TEMA PREORDINATO
P. Marchetti (Roma)

Pre-clinical and clinical aspects of peptide
SERIE DI RELAZIONI SU TEMA PREORDINATO
G. Parmiani (Milano)

13.00 – 14.00
LUNCH

14.00 – 16.30
Dendritic cell-based vaccines
SERIE DI RELAZIONI SU TEMA PREORDINATO
L. Ridolfi (Forli-Cesena)

Immunomodulating antibodies in the treatment of metastatic melanoma
SERIE DI RELAZIONI SU TEMA PREORDINATO
M. Maio (Siena)

Future perspectives in melanoma research.
R. De Maria, Roma
SERIE DI RELAZIONI SU TEMA PREORDINATO
Verification with questionnaire